The study of effects of aqueous extracts of Zataria multiflora (ZM) and Elaeagnus angostifolia (EA) on the volume of stomach of mouse fetus

ZM is a plant used to remedy dyspepsias in pregnant women. EA is a plant used as a stomach and heart tonic, carminative and in remedy of skeletal and muscular ailments. In order to investigate the probable effects of this extracts on the fetus digestive system the current study was examind. Twenty-eight pregnant balb/c mice (25-30 gr) were divided into control, sham and expremental groups (n=7). From 6th to 15th gestation days, food and water of mouses were removed for about 3 hours. The expremental groups were gavaged with 200 mg/kg/day and 640 mg/kg/day aqueous extracts of ZM and EA in 0.5 ml distilled water, respectivly. The sham group was gavaged with equal amount of distilled water. Pregnant mice were dissected in 16th day of pregnancy. Crown-Rump length (CRL) and weight of them were measured. Seven fetuses from different mothers were selected. Five µm transverse serial sections with 75 µm interval were prepared. The Cavalieri method was applied to estimate the volume of different parts of stomach. The significant differences (p